DAA1941 |
Gait width increases |
Physiological |
nervous system |
Mouse |
— |
— |
|
DAA742 |
Motor function impairment evident in altered gait and balance |
Physiological |
nervous system |
Human |
— |
— |
|
DAA1983 |
Critical decline in fine motor hand movements |
Physiological |
nervous system |
Human |
— |
— |
|
DAA1943 |
Motor coordination decreases |
Physiological |
musculoskeletal system, nervous system |
Mouse |
— |
— |
|
DAA757 |
Parkinsonian signs |
Physiological |
nervous system |
Human |
— |
— |
|
DAA715 |
Lipid biosynthesis decreases |
Physiological |
central nervous system |
Human |
— |
— |
|
DAA735 |
Localized increases and decreases in synaptic transmission |
Physiological |
brain |
Human |
— |
— |
|
DAA2595 |
Frequency of somatic mitochondrial mutations increases with age |
Physiological |
brain |
Human |
— |
— |
|
DAA2596 |
Frequency of mitochondrial DNA deletions increases with age |
Physiological |
brain |
Human |
— |
— |
|
DAA786 |
Increased rhinal cortex activity and functional connectivity in tests for verbal familiarity |
Physiological |
brain |
Human |
— |
— |
|
DAA721 |
Neurofibrillary tangles and Lewy bodies in neurons |
Physiological |
brain |
Human |
— |
— |
|
DAA787 |
Increased bilateral anterior frontal activity in memory interference tests |
Physiological |
brain |
Human |
— |
— |
|
DAA2037 |
Decrease in mitochondrial content and oxidative metabolism in cells |
Physiological |
brain |
Mouse |
— |
— |
|
DAA785 |
Reduced hippocampal activity and functional connectivity in tests for verbal familiarity |
Physiological |
brain |
Human |
— |
— |
|
DAA779 |
Prefrontal cortex activation during learning is reduced |
Physiological |
brain |
Human |
— |
— |
|
DAA714 |
Neuronal soma shrinks in size |
Physiological |
brain |
Human |
— |
— |
|
DAA788 |
Viscoelastic modulus of brain tissue decreases |
Physiological |
brain |
Human |
— |
— |
|
DAA763 |
Prolongation of calcium signals in nerve cells |
Physiological |
brain |
Human |
— |
— |
|
DAA780 |
Medial temporal activation during encoding and retrieval of memory is reduced |
Physiological |
brain |
Human |
— |
— |
|
DAA1980 |
Reaction time for a visually paced simple motor task increases with age |
Physiological |
brain |
Human |
— |
— |
|
DAA1949 |
Intracellular glutathione content decreases |
Physiological |
brain |
Mouse |
— |
— |
|
DAA733 |
Neurotransmitter and neuro receptor concentrations are altered |
Physiological |
brain |
Human |
— |
— |
|
DAA1948 |
Neurogenesis is reduced |
Physiological |
brain |
Mouse |
— |
— |
|
DAA783 |
Increased sustained activity in tests of working memory |
Physiological |
brain |
Human |
— |
— |
|
DAA784 |
Increased transient activity in non-spatial auditory working memory test |
Physiological |
brain |
Human |
— |
— |
|